Claude-shaped science

Why it matters here

Matthew Schwartz describes building BootLoops with Claude: reusable scientific software and working protocols that carry tools from one project to another. This is a concrete account of AI-assisted tool development and reuse. Human researchers chose promising directions, redirected the model toward useful questions and checked its conclusions. The open repository documents the resulting harness.

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What to keep in mind

• An author account, not a controlled comparison of research productivity or a demonstrated autonomous self-improvement loop.
• Domain experts supplied direction and validation; the article reports substantial ongoing guidance.
• This entry does not independently verify the claimed scientific discoveries or manuscript counts. The linked NBER working paper was inaccessible during review.
• Schwartz discloses a visiting appointment at Anthropic; BootLoops is owned and maintained by him, not an Anthropic project.